Rhinocerebral mucormycosis: A deadly disease on the rise.
نویسندگان
چکیده
According to WHO, there will be epidemic of diabetes world over and India is going to be 'A diabetes capital of the world' by 2025. With the increasing incidence of diabetes, the associated complications are also bound to increase. Rhinocerebral mucormycosis is one of them.Rhinocerebral Mucormycosis is an opportunistic, fulminating fungal infection, caused by Rhizopus species of order of mucorales, frequently seen in diabetic and immunocompromised patients. Mucormycosis has a very high mortality rate.Early diagnosis and treatment with Amphotericin-B is the key to combat this disease successfully. We have seen 13 cases in last 3 years (2002-2005) in our area. This incidence is significant, as this type of cases were rarely seen before 2002, in this geographical area. We present an account of these cases; treatment strategies adopted, review of literature, and highlight 'the role of ENT surgeon in diagnosis and management of this dreadful disease'.
منابع مشابه
An aggressive multidisciplinary approach reduces mortality in rhinocerebral mucormycosis
BACKGROUND Rhinocerebral mucormycosis occurs in immunocompromised hosts with uncontrolled diabetes, solid organ transplants, and hematologic malignancies. Primary disease is in the paranasal sinuses but often progresses intracranially, via direct extension or angioinvasion. Rhinocerebral mucormycosis is rapidly fatal with a mortality rate of 85%, even when maximally treated with surgical debrid...
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BACKGROUND AND OBJECTIVES Mucormycoses are a group of invasive infections caused by filamentous fungi of the Mucoraceae family, with the rhinocerebral form of the disease being the most common in large case series. In the present paper we review the characteristics of the rhinocerebral form of the disease. EVIDENCE AND INFORMATION SOURCES The present review is based on the analysis of the cur...
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Background and Aim: Mucormycosis is an aggressive and life-threating fungal infection that affects patients with uncontrolled diabetes mellitus (DM) or compromised immune system. The most common symptom of rhinocerebral mucormycosis is sinusitis, and if the infection spreads beyond the sinus, more severe symptoms such as blindness, seizure, and death may occur. Case Presentation: We descri...
متن کاملRhino cerebral mucormycosis . A report of two cases and review of literature
Mucormycosis is caused by fungi of the order Mucorales and is one of the fulminant and fatal mycotic infections known to human beings with a high mortality rate. Rhinocerebral mucormycosis is the most common type and its extension to the orbit and brain is quite usual. It is commonly reported in immunocompromised patients such as poorly controlled diabetes mellitus, blood dyscrasias, malnutriti...
متن کاملگزارش یک مورد موکور مایکوزیس رینوسربرال
Mucormycosis is the most fatal systemic fungal disease which is precipitated by diabetes or immunodeficiency state. The most common form of the disease is the rhinocerebral involvement. The disease has a high rate of mortality if not diagnosed in time and treated properly. This article presents Mucormycosis in a diabetic. The case was a 26 year old young male with diabetes mellitus being treate...
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ورودعنوان ژورنال:
- Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
دوره 59 2 شماره
صفحات -
تاریخ انتشار 2007